← BioTransfer GEO Dataset Finder
GEO series

A core stemness program in exhausted CD8+ T cells

GSE285187 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 24 samples Submitted 2025/04/23 Platform GPL34290Platform GPL24247
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells
Xu J, Jia Z, Zhao X et al. · The Journal of experimental medicine 2025 · PMID 40327039 · doi:10.1084/jem.20241133
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE285187_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 24 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1201764 and SRA study SRP553234. Searching any of these in the dataset finder brings you back here.

Study design
4 × P14 CD8+ T cells sgControl, Day14, vs 4 × P14 CD8+ T cells sgZc3h12a, Day14, vs 4 × P14 CD8+ T cells sgBcor, Day14, vs 4 × P14 CD8+ T cells sgBcor/Zc3h12a, Day14,

Supports a between-group comparison across 16 samples.

4 replicated groups read from 24 sample titles; they account for 16 of them. Check it against the sample list below before relying on it.

Samples in this study
Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.