Basal level of ATF4 promotes T cell readiness for activation-induced proliferation

Direct links to NCBI, no account and no request form: the whole study as GSE305975_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 29 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1308574 and SRA study SRP560230. Searching any of these in the dataset finder brings you back here.

Supports a between-group comparison across 16 samples.

8 replicated groups read from 29 sample titles; they account for 16 of them. Check it against the sample list below before relying on it.

• GSM8759839 Mus CD8+ T cell, WT, 0h
• GSM8759840 Mus CD8+ T cell, KO, 0h
• GSM8759841 Mus CD8+ T cell, WT, 12h , rep1
• GSM8759842 Mus CD8+ T cell, WT, 12h , rep2
• GSM8759843 Mus CD8+ T cell, KO, 12h , rep1
• GSM8759844 Mus CD8+ T cell, KO, 12h , rep2
• GSM8759845 Mus CD8+ T cell, WT, 24h , rep1
• GSM8759846 Mus CD8+ T cell, WT, 24h , rep2
• GSM8759847 Mus CD8+ T cell, KO, 24h , rep1
• GSM8759848 Mus CD8+ T cell, KO, 24h , rep2
• GSM8759849 Mus CD8+ T cell, WT, 48h , rep1
• GSM8759850 Mus CD8+ T cell, WT, 48h , rep2
• GSM8759851 Mus CD8+ T cell, KO, 48h , rep1
• GSM8759852 Mus CD8+ T cell, KO, 48h , rep2
• GSM9187071 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 1, (ChIP)
• GSM9187072 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 2, (ChIP)
• GSM9187073 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 3, (ChIP)
• GSM9187074 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 1, (ChIP)
• GSM9187075 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 2, (ChIP)
• GSM9187076 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 3, (ChIP)
• GSM9187077 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 1, (INPUT)
• GSM9187078 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 2, (INPUT)
• GSM9187079 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 3, (INPUT)
• GSM9187080 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 4, (INPUT)
• GSM9187081 Mus CD8+ T cell, C57BL/6J , active 48h, IgG, (INPUT)
• GSM9187082 Mus CD8+ T cell, KO, active 12h,biol rep 1
• GSM9187083 Mus CD8+ T cell, KO, active 12h,biol rep 2
• GSM9187084 Mus CD8+ T cell, WT, active 12h,biol rep 1
• GSM9187085 Mus CD8+ T cell, WT, active 12h,biol rep 2

• GSE296994 H3K9 di-methylation dynamics underlies mouse minor zygotic genome activation 174 samples
• GSE291274 The placentalia specific histone H3.4 promotes germ cell development and reproductive fitness 167 samples
• GSE333887 Matched single-cell chromatin, transcriptome, and surface marker profiling captures in vivo epigenomic reprogramming during basal-to-luminal transition in the mammary gland [transplantations_OneCell_multiome] 14 samples
• GSE217664 Decoding Trp53 regulatory program in various tissues and organs 404 samples
• GSE312302 NMuMG PBRM1 RNA-seq, ATAC-seq, and ChIP-seq 171 samples
• GSE318069 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation 145 samples
• GSE236580 Adipose tissue retains an epigenetic memory of obesity after weight loss 135 samples
• GSE294389 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis 131 samples

Search all mouse RNA-seq datasets in GEO →