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ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment.

GSE297837 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 126 samples Submitted 2026/05/01 Platform GPL24247
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
ChAHP silences SINE retrotransposons by inhibiting TFIIIB recruitment
Schnabl-Baumgartner J, Mohn F, Schwaiger M et al. · Molecular cell 2026 · PMID 42413492 · doi:10.1016/j.molcel.2026.06.024
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE297837_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 126 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1266251 and SRA study SRP587035. Searching any of these in the dataset finder brings you back here.

Study design
13 conditions, mostly in triplicate
RNA-seq in ADNP-FKBP12 mESC, ctrl, 1h, ×3 RNA-seq in ADNP-FKBP12 mESC, ctrl, 24h, ×3 RNA-seq in ADNP-FKBP12 mESC, ctrl, 4h, ×3 RNA-seq in ADNP-FKBP12 mESC, dTAG13, 24h, ×3 RNA-seq in ADNP-FKBP12 mESC, dTAG13, 4h, ×3 RNA-seq in ADNP-FKBP12 CTCF-FKBP12 mESC, ctrl… ×3 RNA-seq in ADNP-FKBP12 CTCF-FKBP12 mESC, dTAG… ×3 RNA-seq in CTCF-FKBP12 mESC, ctrl, 24h, ×3 +7 more

Supports a between-group comparison across 38 samples.

13 replicated groups read from the first 40 of 126 sample titles; they account for 38 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 86 more — browse all 126 samples with per-sample file links →

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