TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer
Direct links to NCBI, no account and no request form: the whole study as GSE334497_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 10 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1475339 and SRA study SRP707135. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
2 replicated groups read from 10 sample titles; they account for 10 of them. Check it against the sample list below before relying on it.
- GSM9789678 4T1, KO, rep1
- GSM9789679 4T1, KO, rep2
- GSM9789680 4T1, KO, rep3
- GSM9789681 4T1, KO, rep4
- GSM9789682 4T1, KO, rep5
- GSM9789683 4T1, WT, rep1
- GSM9789684 4T1, WT, rep2
- GSM9789685 4T1, WT, rep3
- GSM9789686 4T1, WT, rep4
- GSM9789687 4T1, WT, rep5
- GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
- GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples
- GSE325548 Time-resolved transcriptomic profiling of surgical wounds identifies stage-specific therapeutic targets for residual ovarian cancer 48 samples
- GSE263383 Unbiased niche labeling maps immune-excluded niche in bone metastasis 33 samples
- GSE304945 Tumor-borne ADAMTSL4 drives cancer cachexia via TGFβ signaling pathway 32 samples
- GSE322551 Engineered bacteria as exogenous organelle mimics restore PTEN and p53 tumor suppressor functions for cancer therapy 30 samples
- GSE338763 Inflammatory Neuropathy in Mouse and Primate Models of Colorectal Cancer 24 samples
- GSE269187 ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program [in vitro] 17 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.