GEO series
Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity
GSE306265
Mus musculus
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
106 samples
Submitted 2026/03/20
Platform GPL24247Platform GPL34328Platform GPL19057
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
This dataset
Download
Direct links to NCBI, no account and no request form: the whole study as GSE306265_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 106 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1310302 and SRA study SRP590922. Searching any of these in the dataset finder brings you back here.
Study design
14 conditions, mostly in triplicate
ATAC-seq on P21 V1 astrocyte GR-KO nuclei, ×3
ATAC-seq on P21 V1 astrocyte GR-Con nuclei, ×3
GR CUT&RUN on P14 DR V1 GFP+ astrocytes, ×3
GR CUT&RUN on P14 NR V1 GFP+ astrocytes, ×3
GR CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, ×3
GR CUT&RUN on P14 NR V1 GFP+ inhibitory neuro… ×3
GR CUT&RUN on P14 NR V1 GFP+ excitatory neuro… ×3
NFIA CUT&RUN on P14 NR V1 GFP+ astrocytes, ×3
+8 more
Supports a between-group comparison across 38 samples.
14 replicated groups read from the first 40 of 106 sample titles; they account for 38 of them. Check it against the sample list below before relying on it.
Samples in this study
0 selected
- GSM9037712 ATAC-seq on P21 V1 astrocyte GR-KO nuclei, replicate 1
- GSM9037713 ATAC-seq on P21 V1 astrocyte GR-KO nuclei, replicate 2
- GSM9037714 ATAC-seq on P21 V1 astrocyte GR-KO nuclei, replicate 3
- GSM9037715 ATAC-seq on P21 V1 astrocyte GR-Con nuclei, replicate 1
- GSM9037716 ATAC-seq on P21 V1 astrocyte GR-Con nuclei, replicate 2
- GSM9037717 ATAC-seq on P21 V1 astrocyte GR-Con nuclei, replicate 3
- GSM9195872 GR CUT&RUN on P14 DR V1 GFP+ astrocytes, replicate 1
- GSM9195873 GR CUT&RUN on P14 DR V1 GFP+ astrocytes, replicate 2
- GSM9195875 GR CUT&RUN on P14 DR V1 GFP+ astrocytes, replicate 3
- GSM9195876 GR CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 1
- GSM9195877 GR CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 2
- GSM9195879 GR CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 3
- GSM9195880 GR CUT&RUN on P14 DR V1 GFP- cells, replicate 1
- GSM9195882 GR CUT&RUN on P14 DR V1 GFP- cells, replicate 2
- GSM9195883 GR CUT&RUN on P14 NR V1 GFP- cells, replicate 1
- GSM9195885 GR CUT&RUN on P14 NR V1 GFP- cells, replicate 2
- GSM9195886 IgG CUT&RUN on P14 DR V1 GFP+ astrocytes, replicate 1
- GSM9195887 IgG CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 1
- GSM9195889 GR CUT&RUN on P14 NR V1 GR-Con astrocytes, replicate 1
- GSM9195890 GR CUT&RUN on P14 NR V1 GR-Con astrocytes, replicate 2
- GSM9195892 GR CUT&RUN on P14 NR V1 GR-KO astrocytes, replicate 1
- GSM9195893 GR CUT&RUN on P14 NR V1 GR-KO astrocytes, replicate 2
- GSM9195894 GR CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 1
- GSM9195896 GR CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 2
- GSM9195897 GR CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 3
- GSM9195899 GR CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 1
- GSM9195900 GR CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 2
- GSM9195902 GR CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 3
- GSM9195903 GR CUT&RUN on P14 NR V1 GFP+ excitatory neurons, replicate 1
- GSM9195905 GR CUT&RUN on P14 NR V1 GFP+ excitatory neurons, replicate 2
- GSM9195906 GR CUT&RUN on P14 NR V1 GFP+ excitatory neurons, replicate 3
- GSM9195907 NFIA CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 1
- GSM9195909 NFIA CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 2
- GSM9195910 NFIA CUT&RUN on P14 NR V1 GFP+ astrocytes, replicate 3
- GSM9195912 NFIA CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 1
- GSM9195913 NFIA CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 2
- GSM9195914 NFIA CUT&RUN on P14 NR V1 GFP+ oligodendrocytes, replicate 3
- GSM9195916 NFIA CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 1
- GSM9195917 NFIA CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 2
- GSM9195919 NFIA CUT&RUN on P14 NR V1 GFP+ inhibitory neurons, replicate 3
+ 66 more — browse all 106 samples with per-sample file links →
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