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Lineage Plasticity Driven by GATA6 Loss Fuels Colorectal Cancer Metastasis

GSE290756 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 50 samples Submitted 2026/06/22 Platform GPL30172Platform GPL19057
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE290756_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 50 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1230054 and SRA study SRP687269. Searching any of these in the dataset finder brings you back here.

Study design
8 conditions, mostly with about 6 replicates each
Met1_AKP ×6 Primary2_AKP ×6 Met2_AKP ×6 Primary3_AKP ×6 Met3_AKP ×6 Control ×3 GATA6KO ×3 GATA6KO_GATA6 ×3 +1 more

Supports a between-group comparison across 39 samples.

8 replicated groups read from the first 40 of 50 sample titles; they account for 39 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 10 more — browse all 50 samples with per-sample file links →

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