Multiomic single nuclei profiling of a mouse model of Alzheimer’s disease reveals that ACSS2 confers neuronal resilience to tauopathy
Direct links to NCBI, no account and no request form: the whole study as GSE294332_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 49 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1249036 and SRA study SRP577682. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 39 samples.
14 replicated groups read from the first 40 of 49 sample titles; they account for 39 of them. Check it against the sample list below before relying on it.
- GSM8901194 male-KO-PBS.751
- GSM8901195 male-KO-PBS.752
- GSM8901196 male-KO-PBS.753
- GSM8901197 male-WT-PBS.791
- GSM8901198 male-WT-PBS.792
- GSM8901199 male-WT-PBS.793
- GSM8901200 female-KO-Tau.314
- GSM8901201 female-KO-Tau.324
- GSM8901202 female-KO-Tau.325
- GSM8901203 male-KO-Tau.711
- GSM8901204 male-KO-Tau.712
- GSM8901205 male-KO-Tau.713
- GSM8901206 female-WT-Tau.331
- GSM8901207 female-WT-Tau.341
- GSM8901208 male-WT-Tau.771
- GSM8901209 male-WT-Tau.772
- GSM8901210 male-WT-Tau.773
- GSM8902490 PBS injected control diet 1
- GSM8902491 PBS injected control diet 2
- GSM8902492 PBS injected control diet 3
- GSM8902493 PBS injected acetate diet 1
- GSM8902494 PBS injected acetate diet 2
- GSM8902495 PBS injected acetate diet 3
- GSM8902496 Tau injected control diet 1
- GSM8902497 Tau injected control diet 2
- GSM8902498 Tau injected control diet 3
- GSM8902499 Tau injected acetate diet 1
- GSM8902500 Tau injected acetate diet 2
- GSM8902501 Tau injected acetate diet 3
- GSM8918999 Input.Tau-KO.321
- GSM8919000 Input.Tau-KO.322
- GSM8919001 Input.Tau-KO.323
- GSM8919002 Input.Tau-WT.333
- GSM8919003 Input.Tau-WT.334
- GSM8919004 Input.Tau-WT.335
- GSM8919005 Input.PBS-KO.353
- GSM8919006 Input.PBS-KO.354
- GSM8919007 Input.PBS-WT.362
- GSM8919008 Input.PBS-WT.363
- GSM8919009 H3K27ac.Tau-KO.321
+ 9 more — browse all 49 samples with per-sample file links →
- GSE333807 Single-nucleus multiomic profiling of hippocampus and frontal cortex in a C9orf72 knockout mouse model 52 samples
- GSE190309 Single nuclei RNA and ATAC sequencing of mouse trigeminal ganglia at baseline and in atopic dermatitis-like disease. 14 samples
- GSE306265 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity 106 samples
- GSE293881 Single cell 10X Genomics Multiome Analysis of H3.3K4M Mutant Brain Samples 32 samples
- GSE334540 Single nucleus multiome (RNAseq and ATACseq) of male and female mouse pituitary 32 samples
- GSE314068 Mapping the ISR Landscape in Cognitive Disorders via single-cell multi-omics 28 samples
- GSE333887 Matched single-cell chromatin, transcriptome, and surface marker profiling captures in vivo epigenomic reprogramming during basal-to-luminal transition in the mammary gland [transplantations_OneCell_multiome] 14 samples
- GSE217664 Decoding Trp53 regulatory program in various tissues and organs 404 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.