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LARP6 promotes carcinogenic features of triple negative breast cancer cell line by directly modulating alternative splicing of associated genes

GSE248132 Homo sapiens Other; Expression profiling by high throughput sequencing 10 samples Submitted 2025/03/13 Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
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Published in
The RNA-binding protein LARP6 regulates the alternative splicing of related genes in MDA-MB-231 cells
Guo L, Liu Y, Yan S et al. · Scientific reports 2025 · PMID 40050364 · doi:10.1038/s41598-025-92351-8
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Direct links to NCBI, no account and no request form: the whole study as GSE248132_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 10 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1041805 and SRA study SRP472669. Searching any of these in the dataset finder brings you back here.

Study design
3 × NC vs 3 × OE_LARP6 vs 2 × LARP6-Input vs 2 × LARP6-IP

Supports a between-group comparison across 10 samples.

4 replicated groups read from 10 sample titles; they account for 10 of them. Check it against the sample list below before relying on it.

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