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Deciphering the functional impact of Alzheimer’s Disease-associated variants in resting and proinflammatory immune cells

GSE300844 Homo sapiens Other; Expression profiling by high throughput sequencing 192 samples Submitted 2025/07/02 Platform GPL34281Platform GPL34284Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE300844_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 192 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1282188 and SRA study SRP595538. Searching any of these in the dataset finder brings you back here.

Study design
20 conditions, mostly in duplicate
Replicate 1 Control RNA seq ×2 Replicate 1 Treated RNA seq ×2 Replicate 2 Control RNA seq ×2 Replicate 2 Treated RNA seq ×2 Replicate 3 Control RNA seq ×2 Replicate 3 Treated RNA seq ×2 Replicate 4 Control RNA seq ×2 Replicate 5 Control RNA seq ×2 +12 more

Supports a case/control comparison: 20 samples read as cases, 20 as controls.

20 replicated groups read from the first 40 of 192 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 152 more — browse all 192 samples with per-sample file links →

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