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QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5’splice sites

GSE306691 Homo sapiens Other; Expression profiling by high throughput sequencing 60 samples Submitted 2025/09/17 Platform GPL34284Platform GPL16791
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5' splice sites
Akinyi MV, Yao W, Zeman J et al. · bioRxiv : the preprint server for biology 2025 · PMID 40950209 · doi:10.1101/2025.09.04.674271
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE306691_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 60 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1311820 and SRA study SRP613447. Searching any of these in the dataset finder brings you back here.

Study design
15 conditions, mostly in triplicate
QKI_D0_IP ×3 QKI_D0_input ×3 QKI_D4_IP ×3 QKI_D4_input ×3 QKI_D8_IP ×3 QKI_D8_input ×3 D4-WT ×3 D4-KO ×3 +8 more

Supports a between-group comparison across 39 samples.

15 replicated groups read from the first 40 of 60 sample titles; they account for 39 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 20 more — browse all 60 samples with per-sample file links →

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