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Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.

GSE270126 Homo sapiens Other; Expression profiling by high throughput sequencing 219 samples Submitted 2026/06/22 Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE270126_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 219 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1125058 and SRA study SRP514105. Searching any of these in the dataset finder brings you back here.

Study design
8 conditions, mostly in triplicate
D283_Day4_control ×3 D283_Day4_KDM2B_gRNA10 ×3 D283_Day4_KDM2B_gRNA28 ×3 D283_Day7_control ×3 D283_Day7_KDM2B_gRNA10 ×3 D283_Day7_KDM2B_gRNA28 ×3 DMB006_gRNA10 ×3 DMB006_control ×2 +17 more

Supports a between-group comparison across 23 samples.

8 replicated groups read from the first 40 of 219 sample titles; they account for 23 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 179 more — browse all 219 samples with per-sample file links →

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