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Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain

GSE274836 Homo sapiens Other; Expression profiling by high throughput sequencing 97 samples Submitted 2025/02/19 Platform GPL18573Platform GPL30173
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Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
Huang Y, Verstegen MJAM, Tjalsma SJD et al. · Genes & development 2025 · PMID 39870429 · doi:10.1101/gad.352235.124
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE274836_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 97 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1148149 and SRA study SRP526430. Searching any of these in the dataset finder brings you back here.

Study design
12 × Enhancer vs 12 × MYEOV vs 11 × CCND vs 5 × CTCF

Supports a between-group comparison across 40 samples.

4 replicated groups read from the first 40 of 97 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 57 more — browse all 97 samples with per-sample file links →

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