GEO series
ZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression.
GSE237959
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
36 samples
Submitted 2024/12/26
Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Rane G, Kuan VLS, Wang S et al.
· The EMBO journal 2024
· PMID 39562739
· doi:10.1038/s44318-024-00306-y
This dataset
Download
Direct links to NCBI, no account and no request form: the whole study as GSE237959_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 36 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA997296 and SRA study SRP450801. Searching any of these in the dataset finder brings you back here.
Study design
10 conditions, mostly with about 5 replicates each
U2OS cells, WT, RNA-seq ×5
U2OS cells, ZBTB48 KO, RNA-seq ×5
U2OS cells, WT IFNg, RNA-seq ×5
U2OS cells, ZBTB48 KO IFNg, RNA-seq ×5
U2OS cells, WT H3K4me3 ChIP, ×3
U2OS cells, ZBTB48 KO H3K4me3 ChIP, ×3
U2OS cells, WT input, ×2
U2OS cells, WT FAIRE, ×2
+4 more
Supports a between-group comparison across 34 samples.
10 replicated groups read from 36 sample titles; they account for 34 of them. Check it against the sample list below before relying on it.
Samples in this study
0 selected
- GSM7656923 U2OS cells, WT H3K4me3 ChIP, rep1
- GSM7656924 U2OS cells, WT H3K4me3 ChIP, rep2
- GSM7656925 U2OS cells, WT H3K4me3 ChIP, rep3
- GSM7656926 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep1
- GSM7656927 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep2
- GSM7656928 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep3
- GSM7656929 U2OS cells, WT input, rep1
- GSM7656930 U2OS cells, WT input, rep2
- GSM7656931 U2OS cells, WT FAIRE, rep1
- GSM7656932 U2OS cells, WT FAIRE, rep2
- GSM7656933 U2OS cells, ZBTB48 KO FAIRE, rep1
- GSM7656934 U2OS cells, ZBTB48 KO FAIRE, rep2
- GSM7656935 U2OS cells, WT IFNg FAIRE, rep1
- GSM7656936 U2OS cells, WT IFNg FAIRE, rep2
- GSM7656937 U2OS cells, ZBTB48 KO IFng FAIRE, rep1
- GSM7656938 U2OS cells, ZBTB48 KO IFNg FAIRE, rep2
- GSM7656939 U2OS cells, WT, RNA-seq rep1
- GSM7656940 U2OS cells, WT, RNA-seq rep2
- GSM7656941 U2OS cells, WT, RNA-seq rep3
- GSM7656942 U2OS cells, WT, RNA-seq rep4
- GSM7656943 U2OS cells, WT, RNA-seq rep5
- GSM7656944 U2OS cells, ZBTB48 KO, RNA-seq rep1
- GSM7656945 U2OS cells, ZBTB48 KO, RNA-seq rep2
- GSM7656946 U2OS cells, ZBTB48 KO, RNA-seq rep3
- GSM7656947 U2OS cells, ZBTB48 KO, RNA-seq rep4
- GSM7656948 U2OS cells, ZBTB48 KO, RNA-seq rep5
- GSM7656949 U2OS cells, WT IFNg, RNA-seq rep1
- GSM7656950 U2OS cells, WT IFNg, RNA-seq rep2
- GSM7656951 U2OS cells, WT IFNg, RNA-seq rep3
- GSM7656952 U2OS cells, WT IFNg, RNA-seq rep4
- GSM7656953 U2OS cells, WT IFNg, RNA-seq rep5
- GSM7656954 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep1
- GSM7656955 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep2
- GSM7656956 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep3
- GSM7656957 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep4
- GSM7656958 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep5
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