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DNA repair drives cisplatin-induced neuronal death

GSE329935 Homo sapiens Other; Expression profiling by high throughput sequencing 28 samples Submitted 2026/06/10 Platform GPL30173
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
DNA repair drives cisplatin-induced neuronal death
Nathan WJ, Chen C, Sakr R et al. · Cell 2026 · PMID 42269607 · doi:10.1016/j.cell.2026.05.025
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE329935_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 28 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1462216 and SRA study SRP697604. Searching any of these in the dataset finder brings you back here.

Study design
8 conditions, mostly in duplicate
iNeuron-WT-NT-day14-RNA-seq ×3 iNeuron-WT-20uM-cispt-dN-day14-RNA-seq ×3 241218-iNeuron-WT-NT-SAR-seq ×2 241218-iNeuron-WT-5uM-cisplatin-SAR-seq ×2 241218-iNeuron-WT-20uM-cisplatin-SAR-seq ×2 241218-iNeuron-WT-50uM-cisplatin-SAR-seq ×2 20251210-iNeuron-WT-20uM-cispt-SAR-seq ×2 20251210-iNeuron-WT-20uM-cispt-DRB-SAR-seq ×2 +10 more

Supports a between-group comparison across 18 samples.

8 replicated groups read from 28 sample titles; they account for 18 of them. Check it against the sample list below before relying on it.

Samples in this study
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