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Expression profiling by high throughput sequencing of breast cancer

GSE323973 Homo sapiens Expression profiling by high throughput sequencing 158 samples Submitted 2026/03/07 Platform GPL23227
Summary
This study comprises 158 clinical samples diagnosed as breast carcinoma in situ. Total RNA was extracted from fresh-frozen tissue specimens and subjected to high-throughput RNA sequencing to characterize the transcriptomic landscape and identify molecular signatures associated with disease progression and heterogeneity.
Published in
Quantitative coupling of clonal CNV evolution and spatially restricted malignant states identifies MFGE8 as a candidate late-state-associated target in breast cancer
Ge Z, Wu L, Wang S et al. · Journal of translational medicine 2026 · PMID 42169126 · doi:10.1186/s12967-026-08308-6
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE323973_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 158 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1432817. Searching any of these in the dataset finder brings you back here.

Study design
A cohort of 158 individual samples

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Sample titles run A_001 … A_045 and carry no group information.

Samples in this study

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