← BioTransfer GEO Dataset Finder
GEO series

Targeting p300/CBP abolishes HOXB13 loss-induced lipogenesis and tumor metastasis

GSE296250 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 43 samples Submitted 2025/10/08 Platform GPL20301Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling
Lu X, Keo V, Cheng I et al. · Nature genetics 2025 · PMID 40691407 · doi:10.1038/s41588-025-02265-4
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE296250_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 43 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1258268 and SRA study SRP582834. Searching any of these in the dataset finder brings you back here.

Study design
9 conditions, mostly in duplicate
shCtrl DMSO # ×3 shCtrl CCS1477 # ×3 shHOXB13 DMSO # ×3 shHOXB13 CCS1477 # ×3 shCtrl # ×2 shCtrl+shp300 # ×2 shCtrl+shCBP # ×2 shCtrl+shp300/CBP # ×2 +19 more

Supports a between-group comparison across 22 samples.

9 replicated groups read from the first 40 of 43 sample titles; they account for 22 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 3 more — browse all 43 samples with per-sample file links →

Similar datasets

Search all human ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.