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Loss of METTL3 potentiates transposable element expression and drives inflammation-induced cell plasticity in the mammary epithelium

GSE281124 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 24 samples Submitted 2025/10/28 Platform GPL16791Platform GPL18573
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Published in
METTL3-dependent m6A RNA methylation suppresses aberrant mammary epithelial differentiation and neoplastic transformation
Li Y, Qiu X, Sandusky Z et al. · Proceedings of the National Academy of Sciences of the United States of America 2025 · PMID 41218124 · doi:10.1073/pnas.2514643122
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Direct links to NCBI, no account and no request form: the whole study as GSE281124_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 24 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1182333 and SRA study SRP542697. Searching any of these in the dataset finder brings you back here.

Study design
24 conditions, each sampled once — no replicated groups

Read from 24 sample titles: 24 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study
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