← BioTransfer GEO Dataset Finder
GEO series

Lysine Crotonylation Acts as an Epigenetic Switch for Glutamate Neurotransmission and Spatial Memory

GSE281007 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 12 samples Submitted 2024/11/13 Platform GPL24247
Summary
Using a single-nucleus multiomics approach, this study demonstrates that enhancing histone lysine crotonylation modulates cell type–specific chromatin accessibility and drives the expression of genes encoding key proteins involved in glutamatergic neurotransmission during memory consolidation.
Published in
Histone Lysine Crotonylation Regulates Long-Term Memory Storage
Mukherjee U, Basu B, Beyer SE et al. · bioRxiv : the preprint server for biology 2025 · PMID 40027819 · doi:10.1101/2025.02.19.639114
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE281007_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 12 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1181824 and SRA study SRP543055. Searching any of these in the dataset finder brings you back here.

Study design
12 conditions, each sampled once — no replicated groups

Read from 12 sample titles: 12 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study
Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.