An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility
Direct links to NCBI, no account and no request form: the whole study as GSE249253_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 40 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1048327 and SRA study SRP475599. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 36 samples.
12 replicated groups read from 40 sample titles; they account for 36 of them. Check it against the sample list below before relying on it.
- GSM7932185 ESC, Rep1
- GSM7932186 ESC, Rep2
- GSM7932187 ECTO, Rep1
- GSM7932188 ECTO, Rep2
- GSM7932189 hHAR123, ESC, Rep1
- GSM7932190 hHAR123, ESC, Rep2
- GSM7932191 hHAR123, ESC, Rep3
- GSM7932192 HAR123-KO, ESC, Rep1
- GSM7932193 HAR123-KO, ESC, Rep2
- GSM7932194 HAR123-KO, ESC, Rep3
- GSM7932195 cHAR123, ESC, Rep1
- GSM7932196 cHAR123, ESC, Rep2
- GSM7932197 cHAR123, ESC, Rep3
- GSM7932198 mHAR123, ESC, Rep1
- GSM7932199 mHAR123, ESC, Rep2
- GSM7932200 mHAR123, ESC, Rep3
- GSM7932201 hHAR123, ECTO, Rep1
- GSM7932202 hHAR123, ECTO, Rep2
- GSM7932203 hHAR123, ECTO, Rep3
- GSM7932204 HAR123-KO, ECTO, Rep1
- GSM7932205 HAR123-KO, ECTO, Rep2
- GSM7932206 HAR123-KO, ECTO, Rep3
- GSM7932207 cHAR123, ECTO, Rep1
- GSM7932208 cHAR123, ECTO, Rep2
- GSM7932209 cHAR123, ECTO, Rep3
- GSM7932210 mHAR123, ECTO, Rep1
- GSM7932211 mHAR123, ECTO, Rep2
- GSM7932212 mHAR123, ECTO, Rep3
- GSM7932213 WT, frontal cortex, Rep1
- GSM7932214 WT, frontal cortex, Rep2
- GSM7932215 WT, frontal cortex, Rep3
- GSM7932216 WT, frontal cortex, Rep4
- GSM7932217 HAR123-KO, frontal cortex, Rep1
- GSM7932218 HAR123-KO, frontal cortex, Rep2
- GSM7932219 HAR123-KO, frontal cortex, Rep3
- GSM7932220 HAR123-KO, frontal cortex, Rep4
- GSM7932221 hHAR123, scRNAseq
- GSM7932222 HAR123-KO, scRNAseq
- GSM7932223 cHAR123, scRNAseq
- GSM7932224 mHAR123, scRNAseq
- GSE270434 Bidirectional histone monoaminylation dynamics regulate neural rhythmicity 234 samples
- GSE232555 FOXA2/AP-1 drives prostate cancer lineage plasticity 101 samples
- GSE287355 An EZH2—SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis 79 samples
- GSE295336 H2BE113K mutation promotes breast cancer metastasis through modulating chromatin dynamics 77 samples
- GSE292300 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: ChIP-seq 76 samples
- GSE292302 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: RNA-seq 42 samples
- GSE325427 Integrative single-nucleus multiomic, CUT&Tag, and bulk RNA-seq profiling of human and mouse prefrontal cortex reveals gene regulatory mechanisms of cortical development and Meis2 function 34 samples
- GSE254156 The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumor suppression 25 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.