GEO series
Histone serotonylation regulates ependymoma tumorigenesis through neurodevelopmental pathways
GSE246033
Mus musculus
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
34 samples
Submitted 2024/06/03
Platform GPL19057
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Chen HC, He P, McDonald M et al.
· Nature 2024
· PMID 39085609
· doi:10.1038/s41586-024-07751-z
This dataset
Download
Direct links to NCBI, no account and no request form: the whole study as GSE246033_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 34 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1031155 and SRA study SRP468069. Searching any of these in the dataset finder brings you back here.
Study design
14 conditions, mostly in duplicate
mouse non-tumor cortex tissue, ×3
mouse ZFTA-RELA ependymoma tumor, ×3
mouse ZFTA-RELA ependymoma tumor, ETV5 overex… ×3
mouse ZFTA-RELA ependymoma tumor, NPY overexp… ×3
mouse ZFTA-RELA ependymoma tumor, input (for … ×3
mouse ZFTA-RELA ependymoma tumor, ChIP-5HTH3, ×3
mouse ZFTA-RELA ependymoma tumor, input (for … ×2
mouse ZFTA-RELA ependymoma tumor, ChIP-H3K27a… ×2
+6 more
Supports a between-group comparison across 34 samples.
14 replicated groups read from 34 sample titles; they account for 34 of them. Check it against the sample list below before relying on it.
Samples in this study
0 selected
- GSM7854112 mouse non-tumor cortex tissue, rep1
- GSM7854113 mouse non-tumor cortex tissue, rep2
- GSM7854114 mouse non-tumor cortex tissue, rep3
- GSM7854115 mouse ZFTA-RELA ependymoma tumor, rep1
- GSM7854116 mouse ZFTA-RELA ependymoma tumor, rep2
- GSM7854117 mouse ZFTA-RELA ependymoma tumor, rep3
- GSM7854118 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression rep1
- GSM7854119 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression rep2
- GSM7854120 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression rep3
- GSM7854121 mouse ZFTA-RELA ependymoma tumor, NPY overexpression rep1
- GSM7854122 mouse ZFTA-RELA ependymoma tumor, NPY overexpression rep2
- GSM7854123 mouse ZFTA-RELA ependymoma tumor, NPY overexpression rep3
- GSM7854124 mouse ZFTA-RELA ependymoma tumor, input (for 5HTH3), rep1
- GSM7854125 mouse ZFTA-RELA ependymoma tumor, ChIP-5HTH3, rep1
- GSM7854126 mouse ZFTA-RELA ependymoma tumor, input (for 5HTH3), rep2
- GSM7854127 mouse ZFTA-RELA ependymoma tumor, ChIP-5HTH3, rep2
- GSM7854128 mouse ZFTA-RELA ependymoma tumor, input (for 5HTH3), rep3
- GSM7854129 mouse ZFTA-RELA ependymoma tumor, ChIP-5HTH3, rep3
- GSM7854130 mouse ZFTA-RELA ependymoma tumor, input (for H3K27ac), rep1
- GSM7854131 mouse ZFTA-RELA ependymoma tumor, ChIP-H3K27ac, rep1
- GSM7854132 mouse ZFTA-RELA ependymoma tumor, input (for H3K27ac), rep2
- GSM7854133 mouse ZFTA-RELA ependymoma tumor, ChIP-H3K27ac, rep2
- GSM7854134 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, input (for H3K27ac), rep2
- GSM7854135 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, ChIP-H3K27ac, rep2
- GSM7854136 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, input (for H3K27ac), rep1
- GSM7854137 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, ChIP-H3K27ac, rep1
- GSM7854138 mouse ZFTA-RELA ependymoma tumor, input (for H3K27me3), rep1
- GSM7854139 mouse ZFTA-RELA ependymoma tumor, ChIP-H3K27me3, rep1
- GSM7854140 mouse ZFTA-RELA ependymoma tumor, input (for H3K27me3), rep2
- GSM7854141 mouse ZFTA-RELA ependymoma tumor, ChIP-H3K27me3, rep2
- GSM7854142 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, input (for H3K27me3), rep1
- GSM7854143 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, ChIP-H3K27me3, rep1
- GSM7854144 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, input (for H3K27me3), rep2
- GSM7854145 mouse ZFTA-RELA ependymoma tumor, ETV5 overexpression, ChIP-H3K27me3, rep2
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