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An in situ method for identification of transcriptome-wide protein-RNA interactions in cells

GSE240326 Homo sapiens; Mus musculus Other; Expression profiling by high throughput sequencing 78 samples Submitted 2024/06/13 Platform GPL34382Platform GPL21103Platform GPL30172Platform GPL24676Platform GPL24247Platform GPL30173Platform GPL28352
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
High-sensitivity in situ capture of endogenous RNA-protein interactions in fixed cells and primary tissues
Liang Q, Yu T, Kofman E et al. · Nature communications 2024 · PMID 39152130 · doi:10.1038/s41467-024-50363-4
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE240326_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 78 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1003311 and SRA study SRP473696. Searching any of these in the dataset finder brings you back here.

Study design
12 conditions, mostly in triplicate
RBFOX2_STAMP_APO1_Nb_dilute_1to ×6 PFA_HEK293T_RBFOX2_STAMP ×3 PFA_HEK293T_TDP43_STAMP ×3 PFA_HEK293T_Enzyme_Only ×3 PFA_HEK293T_Buffer_Only ×3 MeOH_HEK293T_RBFOX2 ×3 MeOH_HEK293T_TDP43 ×3 MeOH_HEK293T_Enzyme_only ×3 +5 more

Supports a between-group comparison across 39 samples.

12 replicated groups read from the first 40 of 78 sample titles; they account for 39 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 38 more — browse all 78 samples with per-sample file links →

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