← BioTransfer GEO Dataset Finder
GEO series

Chromatin accessibility profiling of high endothelial cells (HECs) from mouse peripheral lymph node and Peyer's patch by ATAC-seq

GSE342565 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 2 samples Submitted 2026/08/06 Platform GPL37305
Summary
High endothelial venules (HEVs) are specialized blood vessels that mediate lymphocyte entry into secondary lymphoid organs. We performed ATAC-seq on high endothelial cells (HECs) isolated by flow cytometry from mouse peripheral lymph nodes (PLNs, identified by PNAd expression using the MECA-79 antibody) and Peyer's patches (PPs, identified by MAdCAM-1 expression using the MECA-367 antibody) to characterize genome-wide chromatin accessibility and identify HEC-specific cis-regulatory elements.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE342565_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 2 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1508208 and SRA study SRP724507. Searching any of these in the dataset finder brings you back here.

Study design
2 conditions, each sampled once — no replicated groups

Read from 2 sample titles: 2 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study
Similar datasets

Search all mouse ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.