A conserved HAND2-HAND2_OE-SMAD1/5/9 axis drives hepatic stellate cell activation and extracellular matrix overproduction in multiple fibrotic etiologies

Direct links to NCBI, no account and no request form: the whole study as GSE341616_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1503032 and SRA study SRP721795. Searching any of these in the dataset finder brings you back here.

Supports a between-group comparison across 5 samples.

1 replicated groups read from 5 sample titles; they account for 5 of them. Check it against the sample list below before relying on it.

• GSM9913972 HAND2_OE rep1
• GSM9913973 HAND2_OE rep2
• GSM9913974 HAND2_OE rep3
• GSM9913975 HAND2_OE rep4
• GSM9913976 HAND2_OE rep5

• GSE341139 A conserved HAND2-BMP5-SMAD1/5/9 axis drives hepatic stellate cell activation and extracellular matrix overproduction in multiple fibrotic etiologies 10 samples
• GSE309595 Longitudinal Analysis of Multiple Myeloma: Therapeutic Response and Immune Microenvironment Dynamics in the Context of Tumor Heterogeneity [scRNA-seq] 270 samples
• GSE284666 SenCat: Redefining human cell senescence through multiomic profiling of multiple senescent cell types 190 samples
• GSE330029 Temporal changes in metabolism guide oligodendrocyte precursor cell dynamics in aging and multiple sclerosis [BulkRNAseq] 108 samples
• GSE273700 Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia 104 samples
• GSE226176 Expression data of multiple myeloma patients at various stages of disease 23 samples
• GSE271107 Single-cell RNA sequencing of bone marrow aspirate samples from multiple myeloma and its precursor conditions 19 samples
• GSE342301 SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation 8 samples

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