GEO series
Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Respons
GSE317257
Homo sapiens
Other; Expression profiling by high throughput sequencing
35 samples
Submitted 2026/03/19
Platform GPL20795Platform GPL16791Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Malhi NK, Luo Y, Chen M et al.
· Science translational medicine 2026
· PMID 42018669
· doi:10.1126/scitranslmed.adu3761
This dataset
Download
Direct links to NCBI, no account and no request form: the whole study as GSE317257_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 35 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1406544 and SRA study SRP575493. Searching any of these in the dataset finder brings you back here.
Study design
13 conditions, mostly in duplicate
Diabetic mesenteric artery 6 section ×4
Non-Diabetic mesenteric artery intima ×4
Non-Diabetic mesenteric artery 6 section ×3
Diabetic mesenteric artery intima 4 ×3
Scr ×3
TREM2-KD ×3
Non-Diabetic mesenteric artery 7 section ×2
Diabetic mesenteric artery 7 section ×2
+6 more
Supports a between-group comparison across 34 samples.
13 replicated groups read from 35 sample titles; they account for 34 of them. Check it against the sample list below before relying on it.
Samples in this study
0 selected
- GSM8881930 Non-Diabetic mesenteric artery 6 section 1
- GSM8881931 Non-Diabetic mesenteric artery 6 section 2
- GSM8881932 Non-Diabetic mesenteric artery 6 section 3
- GSM8881933 Non-Diabetic mesenteric artery 7 section 1
- GSM8881934 Non-Diabetic mesenteric artery 7 section 2
- GSM8881935 Diabetic mesenteric artery 6 section 1
- GSM8881936 Diabetic mesenteric artery 6 section 2
- GSM8881937 Diabetic mesenteric artery 6 section 3
- GSM8881938 Diabetic mesenteric artery 6 section 4
- GSM8881939 Diabetic mesenteric artery 7 section 1
- GSM8881940 Diabetic mesenteric artery 7 section 2
- GSM8881941 Non-Diabetic mesenteric artery intima 1 replicate 1
- GSM8881942 Non-Diabetic mesenteric artery intima 1 replicate 2
- GSM8881943 Non-Diabetic mesenteric artery intima 2
- GSM8881944 Non-Diabetic mesenteric artery intima 3
- GSM8881945 Non-Diabetic mesenteric artery intima 4
- GSM8881946 Non-Diabetic mesenteric artery intima 5
- GSM8881947 Diabetic mesenteric artery intima 1 replicate 1
- GSM8881948 Diabetic mesenteric artery intima 1 replicate 2
- GSM8881949 Diabetic mesenteric artery intima 2 replicate 1
- GSM8881950 Diabetic mesenteric artery intima 2 replicate 2
- GSM8881951 Diabetic mesenteric artery intima 3
- GSM8881952 Diabetic mesenteric artery intima 4 replicate 1
- GSM8881953 Diabetic mesenteric artery intima 4 replicate 2
- GSM8881954 Diabetic mesenteric artery intima 4 replicate 3
- GSM8881955 Diabetic mesenteric artery intima 5
- GSM8881956 Non-Diabetic mesenteric artery 1
- GSM8881957 Non-Diabetic mesenteric artery 2
- GSM8881958 Diabetic mesenteric artery
- GSM9467039 Scr_rep1
- GSM9467040 Scr_rep2
- GSM9467041 Scr_rep3
- GSM9467042 TREM2-KD-rep1
- GSM9467043 TREM2-KD-rep2
- GSM9467044 TREM2-KD-rep3
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