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Epigenetic reprogramming of stromal cell states underpins pathologic tissue niches in Crohn’s disease

GSE307670 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 148 samples Submitted 2026/06/29 Platform GPL18573Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
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This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE307670_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 148 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1322482 and SRA study SRP618443. Searching any of these in the dataset finder brings you back here.

Study design
8 conditions, mostly with about 4 replicates each
unstimulated ×6 stimulated_Belinostat ×6 stimulated_DMSO ×6 unstim_dmso ×4 combo_dmso ×4 combo_belinostat ×4 combo_gskj4 ×4 IL1B ×2 +4 more

Supports a case/control comparison: 6 samples read as cases, 8 as controls.

8 replicated groups read from the first 40 of 148 sample titles; they account for 36 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 108 more — browse all 148 samples with per-sample file links →

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