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Transcriptional and epigenetic targets of MEF2C in human microglia contribute to cellular functions related to autism risk and age-related disease.

GSE306993 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 76 samples Submitted 2025/10/01 Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
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This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE306993_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 76 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1314090 and SRA study SRP515232. Searching any of these in the dataset finder brings you back here.

Study design
15 conditions, mostly in duplicate
MHS_2H11 ×3 KO_1F37 ×3 KO_2H10 ×3 Ctl_42N ×2 Ctl_71N ×2 Ctl_D4N ×2 MHS_237 ×2 MHS_2H9 ×2 +14 more

Supports a between-group comparison across 33 samples.

15 replicated groups read from the first 40 of 76 sample titles; they account for 33 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 36 more — browse all 76 samples with per-sample file links →

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