SUMOylation orchestrates a metastable heterochromatin state on a MORC3-responsive element to silence IFNB1 at a distance
Direct links to NCBI, no account and no request form: the whole study as GSE292586_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 151 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1240249 and SRA study SRP572189. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
10 replicated groups read from the first 40 of 151 sample titles; they account for 20 of them. Check it against the sample list below before relying on it.
- GSM8861614 BlaER1, WT, DMSO, IFNB1
- GSM8861615 BlaER1, WT, DMSO, SIRE1
- GSM8861616 BlaER1, WT, DMSO, MRE
- GSM8861617 BlaER1, WT, TAK, IFNB1
- GSM8861618 BlaER1, WT, TAK, SIRE1
- GSM8861619 BlaER1, WT, TAK, MRE
- GSM8861620 BlaER1, STATKO, DMSO, IFNB1
- GSM8861621 BlaER1, STATKO, DMSO, SIRE1
- GSM8861622 BlaER1, STATKO, DMSO, MRE
- GSM8861623 BlaER1, STATKO, TAK, IFNB1
- GSM8861624 BlaER1, STATKO, TAK, SIRE1
- GSM8861625 BlaER1, STATKO, TAK, MRE
- GSM8861626 BlaER1, STATKO, LPS, IFNB1
- GSM8861627 BlaER1, STATKO, LPS, SIRE1
- GSM8861628 BlaER1, STATKO, LPS, MRE
- GSM8861629 BlaER1, STATKO, TAKdMRE, IFNB1
- GSM8861630 BlaER1, STATKO, TAKdMRE, SIRE1
- GSM8861631 BlaER1, STATKO, TAKdMRE, MRE
- GSM8861632 Serie1, RAW 264.7, Input, REP1
- GSM8861633 Serie1, RAW 264.7, Input, REP2
- GSM8861634 Serie1, RAW 264.7, 24h ML, Input, REP1
- GSM8861635 Serie1, RAW 264.7, 24h ML, Input, REP2
- GSM8861636 Serie1,RAW 264.7, DMSO, ChIP H3.3, REP1
- GSM8861637 Serie1, RAW 264.7, DMSO, ChIP H3.3, REP2
- GSM8861638 Serie1, RAW 264.7, 24h ML, ChIP H3.3, REP1
- GSM8861639 Serie1, RAW 264.7, 24h ML, ChIP H3.3, REP2
- GSM8861640 Serie2, RAW 264.7, Input, REP1
- GSM8861641 Serie2, RAW 264.7, Input, REP2
- GSM8861642 Serie2, RAW 264.7, ChIP Morc3, REP1
- GSM8861643 Serie2, RAW 264.7, ChIP Morc3, REP2
- GSM8861644 Serie3, RAW 264.7, Input, REP1
- GSM8861645 Serie3, RAW 264.7, Input, REP2
- GSM8861646 Serie3, RAW 264.7, 24h ML, Input, REP1
- GSM8861647 Serie3, RAW 264.7, 24h ML, Input, REP2
- GSM8861648 Serie3, RAW 264.7, ChIP SUMO2/3, REP1
- GSM8861649 Serie3, RAW 264.7, ChIP SUMO2/3, REP2
- GSM8861650 Serie3, RAW 264.7, DMSO, ChIP H3K9me3, REP1
- GSM8861651 Serie3, RAW 264.7, DMSO, ChIP H3K9me3, REP2
- GSM8861652 Serie3, RAW 264.7, 24h ML, ChIP H3K9me3, REP1
- GSM8861653 Serie3, RAW 264.7, 24h ML, ChIP H3K9me3, REP2
+ 111 more — browse all 151 samples with per-sample file links →
- GSE333685 Vascular smooth muscle cell state trajectories mediate molecular mechanisms of coronary disease risk 64 samples
- GSE301111 Dissecting cellular state alterations critical for the synergistic response and therapy resistance of the combined Abemaciclib, Temozolomide, and Radiation in DIPG PDOX models 14 samples
- GSE218866 ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats [RNA-Seq] 12 samples
- GSE274495 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis. 421 samples
- GSE289420 Astrocyte-derived cholesterol drives synaptic gene expression in developing neurons and reciprocal astrocytic transcriptional programs 416 samples
- GSE320162 Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity [RNA-Seq] 347 samples
- GSE317764 High-Fat Diet Causes Rapid Loss of Intestinal Group 3 Innate Lymphoid Cells Through Microbiota-Driven Inflammation 270 samples
- GSE281472 Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis 245 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.