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Modularity of OCT4 underlies its functional diversity in reprogramming and embryonic development.

GSE286923 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 19 samples Submitted 2025/06/19 Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
Ozkan B, de Anda MR, Hall-Ponsele E et al. · Nature communications 2025 · PMID 41028752 · doi:10.1038/s41467-025-63806-3
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE286923_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 19 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1210538 and SRA study SRP557858. Searching any of these in the dataset finder brings you back here.

Study design
16 conditions, each sampled once — no replicated groups
hFib, ATAC-seq, ×2 OSKM48h, STAT3_siRNA, ATAC-seq, ×2 OSKM48h, TNIP2_siRNA, ATAC-seq, ×2

Read from 19 sample titles: 16 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study
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