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FOXA1 loss drives basal/squamous de-differentiation of prostate cancer and induces an immunosuppressive tumor microenvironment

GSE282726 Homo sapiens; Mus musculus Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 25 samples Submitted 2026/02/21 Platform GPL30172Platform GPL24247Platform GPL33484Platform GPL34290
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Published in
FOXA1 loss drives basal/squamous de-differentiation of prostate cancer and induces an immunosuppressive tumor microenvironment
Brea L, Shi H, Keo V et al. · Nature communications 2026 · PMID 41904157 · doi:10.1038/s41467-026-71121-8
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Direct links to NCBI, no account and no request form: the whole study as GSE282726_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 25 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1190070 and SRA study SRP656839. Searching any of these in the dataset finder brings you back here.

Study design
21 conditions, each sampled once — no replicated groups
P ×3 PF ×3

Read from 25 sample titles: 21 distinct titles with little repetition. Check it against the sample list below before relying on it.

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