Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer

Direct links to NCBI, no account and no request form: the whole study as GSE264145_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 12 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1101055 and SRA study SRP502141. Searching any of these in the dataset finder brings you back here.

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• GSE242839 PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity 29 samples
• GSE310025 Intrinsic RB activation induces tumoral and stromal anti-tumor responses that limit triple-negative breast cancer [RNA-Seq] 28 samples
• GSE245949 Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer 24 samples
• GSE281472 Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis 245 samples
• GSE292302 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: RNA-seq 42 samples
• GSE254156 The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumor suppression 25 samples
• GSE270229 Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties 18 samples
• GSE289420 Astrocyte-derived cholesterol drives synaptic gene expression in developing neurons and reciprocal astrocytic transcriptional programs 416 samples

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