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Competition between two HUSH complexes orchestrates the immune response to retroelement invasion

GSE268799 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 45 samples Submitted 2024/07/15 Platform GPL24676
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Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Competition between two HUSH complexes orchestrates the immune response to retroelement invasion
Danac JMC, Matthews RE, Gungi A et al. · Molecular cell 2024 · PMID 39013473 · doi:10.1016/j.molcel.2024.06.020
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE268799_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 45 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1118759 and SRA study SRP511067. Searching any of these in the dataset finder brings you back here.

Study design
33 conditions, each sampled once — no replicated groups
CRISPRi-HUSH2, sgAAVS1, ×3 CRISPRi-HUSH2, dCas9, ×2 CRISPRi-IRF2, dCas9, ×2 CRISPRi-IRF2, sgAAVS1, ×2 CRISPRi-IRF2, sg1-IRF2, ×2 CRISPRi-IRF2, sg2-IRF2, ×2

Read from the first 40 of 45 sample titles: 33 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study

+ 5 more — browse all 45 samples with per-sample file links →

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