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Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis

GSE267904 Mus musculus Expression profiling by high throughput sequencing 24 samples Submitted 2024/05/21 Platform GPL24247
Summary
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis and limited treatment options. Efforts to identify effective treatments are thwarted by limited understanding of IPF pathogenesis and poor translatability of available preclinical models. To address these limitations, we generated spatially resolved transcriptome maps of human IPF and bleomycin-induced mouse lung fibrosis.
Published in
Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis
Franzén L, Olsson Lindvall M, Hühn M et al. · Nature genetics 2024 · PMID 38951642 · doi:10.1038/s41588-024-01819-2
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Direct links to NCBI, no account and no request form: the whole study as GSE267904_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 24 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1113613 and SRA study SRP508758. Searching any of these in the dataset finder brings you back here.

Study design
3 × d7, ctrl, vs 3 × d7, bleo, vs 3 × d21, ctrl, vs 3 × d21, bleo,

Supports a between-group comparison across 12 samples.

4 replicated groups read from 24 sample titles; they account for 12 of them. Check it against the sample list below before relying on it.

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