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Hypertension Promotes Neuroinflammation, Brain Injury and Cognitive Impairment

GSE261492 Mus musculus Expression profiling by high throughput sequencing 48 samples Submitted 2025/12/31 Platform GPL24247
Summary
We tested the effect of hydralazine on hypertension-induced transciptomic changes in hippocampus and a whole brain hemisphere.
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE261492_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 48 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1087309 and SRA study SRP495001. Searching any of these in the dataset finder brings you back here.

Study design
7 conditions, mostly with about 6 replicates each
A ×6 AH ×6 V ×6 VH ×6 Hippo_A ×6 Hippo_AH ×6 Hippo_V ×4

Supports a between-group comparison across 40 samples.

7 replicated groups read from the first 40 of 48 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 8 more — browse all 48 samples with per-sample file links →

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