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The transcriptional role of TG2-mediated H3Q5ser in CRC [ChIP-seq]

GSE229843 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 16 samples Submitted 2025/04/01 Platform GPL20795
Summary
We investigated the alteration of H2Bub1, H3K4me3, and H3Q5ser upon RNF40-depleted or TG2-depleted HCT116 cells.
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Direct links to NCBI, no account and no request form: the whole study as GSE229843_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 16 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA956437 and SRA study SRP432963. Searching any of these in the dataset finder brings you back here.

Study design
8 conditions, mostly in duplicate
HCT116, H2Bub1, CST, siControl, ×2 HCT116, H2Bub1, CST, siRNF40, ×2 HCT116, H3K4me3, Abclonal, siControl, ×2 HCT116, H3K4me3, Abclonal, siRNF40, ×2 HCT116, H3K4me3, Abclonal, siTG2, ×2 HCT116, H3Q5ser, Sigma, siControl, ×2 HCT116, H3Q5ser, Sigma, siRNF40, ×2 HCT116, H3Q5ser, Sigma, siTG2, ×2

Supports a between-group comparison across 16 samples.

8 replicated groups read from 16 sample titles; they account for 16 of them. Check it against the sample list below before relying on it.

Samples in this study
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