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The evolution of the type I IFN transcriptional response across human populations

GSE217313 Homo sapiens Other; Expression profiling by high throughput sequencing 46 samples Submitted 2026/07/29 Platform GPL18573
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
An intronic LINE-1 regulates IFNAR1 expression in human immune cells
Buttler CA, Ramirez D, Dowell RD et al. · Mobile DNA 2023 · PMID 38037122 · doi:10.1186/s13100-023-00308-3
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE217313_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 46 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA898370 and SRA study SRP406336. Searching any of these in the dataset finder brings you back here.

Study design
17 conditions, mostly in duplicate
PRO-seq, Dave, BSA, 1 hour, ×3 PRO-seq, Eric, BSA, 1 hour, ×3 PRO-seq, Ethan, BSA, 1 hour, ×3 PRO-seq, Dave, IFNB, 1 hour, ×3 PRO-seq, Eric, IFNB, 1 hour, ×3 PRO-seq, Ethan, IFNB, 1 hour, ×3 PRO-seq, GM12878, BSA, 1 hour, ×2 PRO-seq, GM18489, BSA, 1 hour, ×2 +9 more

Supports a between-group comparison across 40 samples.

17 replicated groups read from the first 40 of 46 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 6 more — browse all 46 samples with per-sample file links →

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