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Insights into intestinal neuroendocrine tumors in relation to normal human EEC differentiation

GSE277215 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing 53 samples Submitted 2026/04/29 Platform GPL20795Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny
Singh PN, Hadj Bachir E, Howe JR et al. · The Journal of clinical investigation 2026 · PMID 42166365 · doi:10.1172/JCI197772
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE277215_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 53 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1161190 and SRA study SRP532737. Searching any of these in the dataset finder brings you back here.

Study design
31 conditions, each sampled once — no replicated groups
DFCI SINET ×3 DFCI SINET2 ×2 DFCI SINET8 ×2 DFCI SINET10 ×2 DFCI SINET17 ×2 DFCI SINET18 ×2 DFCI SINET20 ×2 DFCI SINET23 ×2

Read from the first 40 of 53 sample titles: 31 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study

+ 13 more — browse all 53 samples with per-sample file links →

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