A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease
Direct links to NCBI, no account and no request form: the whole study as GSE252238_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 23 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1058989 and SRA study SRP480623. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 4 samples read as cases, 6 as controls.
7 replicated groups read from 23 sample titles; they account for 17 of them. Check it against the sample list below before relying on it.
- GSM7997911 CAGG_A455D
- GSM7997912 CAGG_WT_rep1
- GSM7997913 CAGG_WT_rep2
- GSM7997914 CAGG_WT_rep3
- GSM7997915 DS_A455D_rep1
- GSM7997916 DS_A455D_rep2
- GSM7997917 DS_A455D_rep3
- GSM7997918 DS_WT_rep1
- GSM7997919 DS_WT_rep2
- GSM7997920 WT_A455D_rep1
- GSM7997921 WT_A455D_rep2
- GSM7997922 WT_A455D_rep3
- GSM7997923 WT_WT_rep1
- GSM7997924 WT_WT_rep2
- GSM7997925 DS A455D PMPs transplanted, Cont-tau treated
- GSM7997926 DS A455D PMPs transplanted, DSAD-tau treated
- GSM7997927 WT A455D PMPs and CAGG WT PMPs co-transplanted, Cont-tau treated
- GSM7997928 WT A455D PMPs and CAGG WT PMPs co-transplanted, DSAD-tau treated, replication 1
- GSM7997929 WT A455D PMPs and CAGG WT PMPs co-transplanted, DSAD-tau treated, replication 2
- GSM8606171 DS A455D PMPs transplanted, DSAD-tau treated, 10 mo, rep 1
- GSM8606172 DS A455D PMPs transplanted, DSAD-tau treated, 10 mo, rep 2
- GSM8607474 ND20 CR5 iPSC WGS
- GSM8607475 CAGG WT ESC WGS
- GSE274037 A microglia clonal inflammatory disorder in Alzheimer’s Disease 54 samples
- GSE288077 Metabolic dysfunction-associated steatotic liver disease may increase intrahepatic interferon gene signatures in patients with chronic hepatitis B 35 samples
- GSE342640 Insulin resistance is associated with mammary mitochondrial dysfunction at the onset of human lactation 159 samples
- GSE274229 Evolution of myeloid-mediated immunotherapy resistance in prostate cancer 52 samples
- GSE324329 A kidney-protective mechanism via cellular oxidative stress reduction induced by CD5L protein 38 samples
- GSE294216 Resistance to the KRASG12D Inhibitor MRTX1133 is Associated with Aberrant Histone Acetylation and Increased Sensitivity to BET Inhibition 36 samples
- GSE307527 ARID1A and ARID1B preserve B cell identity, prevent myeloid transformation and reveal therapeutic vulnerabilities 30 samples
- GSE242839 PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity 29 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.