← BioTransfer GEO Dataset Finder
GEO series

m6A alters ribosome dynamics to initiate mRNA degradation

GSE249257 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing; Other 36 samples Submitted 2025/05/09 Platform GPL24247Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
m(6)A alters ribosome dynamics to initiate mRNA degradation
Murakami S, Olarerin-George AO, Liu JF et al. · Cell 2025 · PMID 40328256 · doi:10.1016/j.cell.2025.04.020
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE249257_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 36 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1048343 and SRA study SRP475616. Searching any of these in the dataset finder brings you back here.

Study design
10 conditions, mostly in triplicate
wt_ctrl ×6 ko_ctrl ×6 wt_starv ×3 ko_starv ×3 wt_emt ×3 ko_emt ×3 siNC_ctrl ×3 siNC_emt ×3 +2 more

Supports a between-group comparison across 36 samples.

10 replicated groups read from 36 sample titles; they account for 36 of them. Check it against the sample list below before relying on it.

Samples in this study
Similar datasets

Search all RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.