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DDX41 heterozygosity impairs hematopoietic progenitor cell fitness and cooperates with p53 mutation to drive malignancy

GSE247409 Mus musculus; Homo sapiens Expression profiling by high throughput sequencing 26 samples Submitted 2024/06/13 Platform GPL24247Platform GPL24676
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Summary
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This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE247409_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 26 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1037498 and SRA study SRP471122. Searching any of these in the dataset finder brings you back here.

Study design
6 conditions, mostly in triplicate
Ddx41-WT ×4 Ddx41-WT;p53-WT, WTWT ×3 Ddx41-WT;p53-HET, WTHET ×3 Ddx41-HET ×3 Ddx41-HET;p53-WT, HETWT ×2 Ddx41-HET;p53-HET, HETHET ×2 Sh-Control_38A ×1 sh-Control_38B ×1 +7 more

Supports a between-group comparison across 17 samples.

6 replicated groups read from 26 sample titles; they account for 17 of them. Check it against the sample list below before relying on it.

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