Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models
Direct links to NCBI, no account and no request form: the whole study as GSE240497_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 66 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1003913 and SRA study SRP457573. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 29 samples.
12 replicated groups read from the first 40 of 66 sample titles; they account for 29 of them. Check it against the sample list below before relying on it.
- GSM7698844 U937_DMSO_Replicate_1
- GSM7698845 U937_DMSO_Replicate_2
- GSM7698846 U937_FICZ_Replicate_1
- GSM7698847 U937_FICZ_Replicate_2
- GSM7698848 K562_EV_DMSO
- GSM7698849 K562_AHR_WT_FICZ
- GSM7698850 U937_DMSO_Rep1
- GSM7698851 U937_DMSO_Rep2
- GSM7698852 U937_FICZ_Rep1
- GSM7698853 U937_FICZ_Rep2
- GSM7698854 U937_JQ1_Rep1
- GSM7698855 U937_JQ1_Rep2
- GSM7698856 U937_COMBO_Rep1
- GSM7698857 U937_COMBO_Rep2
- GSM7698858 K562_EV_DMSO_Rep1
- GSM7698859 K562_EV_DMSO_Rep2
- GSM7698860 K562_EV_FICZ_Rep1
- GSM7698861 K562_EV_FICZ_Rep2
- GSM7698862 K562_EV_JQ1_Rep1
- GSM7698863 K562_EV_JQ1_Rep2
- GSM7698864 K562_EV_COMBO_Rep1
- GSM7698865 K562_EV_COMBO_Rep2
- GSM7698866 K562_OE_DMSO_Rep1
- GSM7698867 K562_OE_DMSO_Rep2
- GSM7698868 K562_OE_FICZ_Rep1
- GSM7698869 K562_OE_FICZ_Rep2
- GSM7698870 K562_OE_JQ1_Rep1
- GSM7698871 K562_OE_JQ1_Rep2
- GSM7698872 K562_OE_COMBO_Rep1
- GSM7698873 K562_OE_COMBO_Rep2
- GSM7745910 AML2_24hr_DMSO_1_S1
- GSM7745911 AML2_24hr_DMSO_2_S2
- GSM7745912 AML2_24hr_DMSO_3_S3
- GSM7745913 AML2_24hr_FICZ_1_S4
- GSM7745914 AML2_24hr_FICZ_2_S5
- GSM7745915 AML2_24hr_FICZ_3_S6
- GSM7745916 AML2_24hr_JQ1_1_S7
- GSM7745917 AML2_24hr_JQ1_2_S8
- GSM7745918 AML2_24hr_JQ1_3_S9
- GSM7745919 AML2_24hr_Combo_1_S10
+ 26 more — browse all 66 samples with per-sample file links →
- GSE262166 Treatment of cholangiocarcinoma using humanized monoclonal antibodies targeting Claudin-1 77 samples
- GSE240492 Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells 41 samples
- GSE310479 Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis 38 samples
- GSE248287 Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia 34 samples
- GSE333486 CAR design equips diverse immune cells with unique antigen-specific activation identities 26 samples
- GSE239858 BRCA2 suppresses “head-on” transcription-replication conflicts incurred by dormant origin firing at transcription termination sites 14 samples
- GSE290408 Comprehensive profiling of N6-methyladnosine (m6A) readouts reveals novel m6A readers that regulate human embryonic stem cell differentiation [GLORI-seq] 12 samples
- GSE306057 ALKBH5-IGF2BP2 Axis Mediates Prostate Cancer Progression and Docetaxel Resistance via m6A-Stabilized CLSPN RNA 12 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.