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ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats [ChIP-Seq]

GSE218862 Homo sapiens; Mus musculus Genome binding/occupancy profiling by high throughput sequencing 20 samples Submitted 2025/01/30 Platform GPL18573Platform GPL19057
Summary
ZBTB24 has emerged as a key player in DNA methylation, immunity and development. To explore these multiple facets of ZBTB24 functions, we performed and integrated multi-omics analyses in mouse and human cellular systems relevant for the physiopathological features of the ICF2 syndrome, a rare genetic disease caused by ZBTB24 mutations.
Published in
ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats
Grillo G, Boyarchuk E, Mihic S et al. · Human molecular genetics 2025 · PMID 39562305 · doi:10.1093/hmg/ddae163
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Also filed as BioProject PRJNA906043 and SRA study SRP410201. Searching any of these in the dataset finder brings you back here.

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