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Effect of ZIC1 on group 3 medulloblastoma cell lines and granule neuron progenitor

GSE217639 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 49 samples Submitted 2024/09/19 Platform GPL30172Platform GPL16791Platform GPL24247Platform GPL24676
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
Published in
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Lee JJY, Tao R, You Z et al. · Nature genetics 2025 · PMID 39753768 · doi:10.1038/s41588-024-02014-z
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE217639_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 49 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA899864 and SRA study SRP407041. Searching any of these in the dataset finder brings you back here.

Study design
30 conditions, each sampled once — no replicated groups
D425_RNA_BFP ×3 D425_RNA_ZIC1_4 ×3 ATOH1_GFP_RNA_mch_bulk ×2 ATOH1_GFP_RNA_mch_sort ×2 ATOH1_GFP_RNA_ZIC1_bulk ×2 ATOH1_GFP_RNA_ZIC1_sort ×2 GNP_ZIC1NF_301_IP ×2 GNP_ZIC1NF_WT1_IP ×2

Read from the first 40 of 49 sample titles: 30 distinct titles with little repetition. Check it against the sample list below before relying on it.

Samples in this study

+ 9 more — browse all 49 samples with per-sample file links →

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