GEO series
Rheumatoid Arthritis circulating CD14+ monocytes are epigenetically primed [ChIP-seq]
GSE294235
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
75 samples
Submitted 2025/04/10
Platform GPL18573
Summary
Peripheral blood samples were collected from healthy controls and rheumatoid arthritis patients (active disease: DAS28 > 2.7), subsequently CD14+ monocytes were isolated using a positive selection kit, ChIP-Seq was completed for H3K4me3 and H3K27me3.
Published in
Marzeda AM, Schwenzer A, Didov BS et al.
· Annals of the rheumatic diseases 2025
· PMID 40350372
· doi:10.1016/j.ard.2025.03.016
This dataset
Download
Direct links to NCBI, no account and no request form: the whole study as GSE294235_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 75 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1248776 and SRA study SRP577658. Searching any of these in the dataset finder brings you back here.
Study design
40 conditions, each sampled once — no replicated groups
Read from the first 40 of 75 sample titles: 40 distinct titles with little repetition. Check it against the sample list below before relying on it.
Samples in this study
0 selected
- GSM8900692 Peripheral blood CD14+ monocyte, Healthy Control, Rep1 - Input
- GSM8900693 Peripheral blood CD14+ monocyte, Healthy Control, Rep1 - H3K4me3
- GSM8900694 Peripheral blood CD14+ monocyte, Healthy Control, Rep1 - H3K27me3
- GSM8900695 Peripheral blood CD14+ monocyte, Healthy Control, Rep2 - Input
- GSM8900696 Peripheral blood CD14+ monocyte, Healthy Control, Rep2 - H3K4me3
- GSM8900697 Peripheral blood CD14+ monocyte, Healthy Control, Rep2 - H3K27me3
- GSM8900698 Peripheral blood CD14+ monocyte, Healthy Control, Rep3 - Input
- GSM8900699 Peripheral blood CD14+ monocyte, Healthy Control, Rep3 - H3K4me3
- GSM8900700 Peripheral blood CD14+ monocyte, Healthy Control, Rep3 - H3K27me3
- GSM8900701 Peripheral blood CD14+ monocyte, Healthy Control, Rep4 - Input
- GSM8900702 Peripheral blood CD14+ monocyte, Healthy Control, Rep4 - H3K4me3
- GSM8900703 Peripheral blood CD14+ monocyte, Healthy Control, Rep4 - H3K27me3
- GSM8900704 Peripheral blood CD14+ monocyte, Healthy Control, Rep5 - Input
- GSM8900705 Peripheral blood CD14+ monocyte, Healthy Control, Rep5 - H3K4me3
- GSM8900706 Peripheral blood CD14+ monocyte, Healthy Control, Rep5 - H3K27me3
- GSM8900707 Peripheral blood CD14+ monocyte, Healthy Control, Rep6 - Input
- GSM8900708 Peripheral blood CD14+ monocyte, Healthy Control, Rep6 - H3K4me3
- GSM8900709 Peripheral blood CD14+ monocyte, Healthy Control, Rep6 - H3K27me3
- GSM8900710 Peripheral blood CD14+ monocyte, Healthy Control, Rep7 - Input
- GSM8900711 Peripheral blood CD14+ monocyte, Healthy Control, Rep7 - H3K4me3
- GSM8900712 Peripheral blood CD14+ monocyte, Healthy Control, Rep7 - H3K27me3
- GSM8900713 Peripheral blood CD14+ monocyte, Healthy Control, Rep8 - Input
- GSM8900714 Peripheral blood CD14+ monocyte, Healthy Control, Rep8 - H3K4me3
- GSM8900715 Peripheral blood CD14+ monocyte, Healthy Control, Rep8 - H3K27me3
- GSM8900716 Peripheral blood CD14+ monocyte, Healthy Control, Rep9 - Input
- GSM8900717 Peripheral blood CD14+ monocyte, Healthy Control, Rep9 - H3K4me3
- GSM8900718 Peripheral blood CD14+ monocyte, Healthy Control, Rep9 - H3K27me3
- GSM8900719 Peripheral blood CD14+ monocyte, Healthy Control, Rep10 - Input
- GSM8900720 Peripheral blood CD14+ monocyte, Healthy Control, Rep10 - H3K4me3
- GSM8900721 Peripheral blood CD14+ monocyte, Healthy Control, Rep10 - H3K27me3
- GSM8900722 Peripheral blood CD14+ monocyte, Healthy Control, Rep11 - Input
- GSM8900723 Peripheral blood CD14+ monocyte, Healthy Control, Rep11 - H3K4me3
- GSM8900724 Peripheral blood CD14+ monocyte, Healthy Control, Rep11 - H3K27me3
- GSM8900725 Peripheral blood CD14+ monocyte, Healthy Control, Rep12 - Input
- GSM8900726 Peripheral blood CD14+ monocyte, Healthy Control, Rep12 - H3K4me3
- GSM8900727 Peripheral blood CD14+ monocyte, Healthy Control, Rep12 - H3K27me3
- GSM8900728 Peripheral blood CD14+ monocyte, Healthy Control, Rep13 - Input
- GSM8900729 Peripheral blood CD14+ monocyte, Healthy Control, Rep13 - H3K4me3
- GSM8900730 Peripheral blood CD14+ monocyte, Healthy Control, Rep13 - H3K27me3
- GSM8900731 Peripheral blood CD14+ monocyte, Healthy Control, Rep14 - Input
+ 35 more — browse all 75 samples with per-sample file links →
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