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Role of ATF4 in regulation of kidney gene expressions, signaling pathways and functions

GSE291049 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing 23 samples Submitted 2025/06/25 Platform GPL34284Platform GPL24247
SuperSeries — this record groups several sub-series.
Summary
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Published in
Deletion of the transcription factor ATF4 in a model of clear cell renal cell carcinoma
Chi Y, Chikara S, Aguila EMD et al. · Neoplasia (New York, N.Y.) 2025 · PMID 40472739 · doi:10.1016/j.neo.2025.101188
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Direct links to NCBI, no account and no request form: the whole study as GSE291049_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 23 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1231456 and SRA study SRP567824. Searching any of these in the dataset finder brings you back here.

Study design
6 conditions, mostly in triplicate
WT ×5 GCERAd ×5 GCERAdT ×4 TRACK ×3 RCC4P ×3 RCC4A ×3

Supports a between-group comparison across 23 samples.

6 replicated groups read from 23 sample titles; they account for 23 of them. Check it against the sample list below before relying on it.

Samples in this study
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