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Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response

GSE289193 Mus musculus; Homo sapiens Expression profiling by high throughput sequencing 160 samples Submitted 2026/04/26 Platform GPL24676Platform GPL24247
SuperSeries — this record groups several sub-series.
Summary
This SuperSeries is composed of the SubSeries listed below.
This dataset
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Direct links to NCBI, no account and no request form: the whole study as GSE289193_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 160 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1221875 and SRA study SRP562928. Searching any of these in the dataset finder brings you back here.

Study design
15 conditions, mostly in duplicate
SUM149_Xenograft_Vehicle_Tumo ×4 SUM149_Xenograft_A196_Tumo ×4 SUM149_Xenograft_17AAG_Tumo ×3 SUM149_Xenograft_Combination_Tumo ×3 4T1_DMSO_Tumo ×3 4T1_A196_Tumo ×3 EMT6_DMSO_Tumo ×3 EMT6_A196_Tumo ×3 +7 more

Supports a between-group comparison across 40 samples.

15 replicated groups read from the first 40 of 160 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.

Samples in this study

+ 120 more — browse all 160 samples with per-sample file links →

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