Targeting VRK2 Enhances the Efficacy of Anti-PD-1 Therapy in Hepatocellular Carcinoma by Reducing Direct Phosphorylation and Stability of MYC: CUT-TAG sequencing for MYC in hepatocellular carcinoma cells
Direct links to NCBI, no account and no request form: the whole study as GSE278073_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 16 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1165406 and SRA study SRP534884. Searching any of these in the dataset finder brings you back here.
Read from 16 sample titles: 16 distinct titles with little repetition. Check it against the sample list below before relying on it.
- GSM8539248 MHCC97H-1-IgG, IgG CUT-&TAG
- GSM8539249 MHCC97H-1-siNC, MYC CUT-&TAG
- GSM8539250 MHCC97H-1-siMYC, MYC CUT-&TAG
- GSM8539251 MHCC97H-1-siMYC+MYC WT, MYC CUT-&TAG
- GSM8539252 MHCC97H-1-siMYC+MYC281A, MYC CUT-&TAG
- GSM8539253 MHCC97H-1-siMYC+MYC281D, MYC CUT-&TAG
- GSM8539254 MHCC97H-1-siMYC+MYC293A, MYC CUT-&TAG
- GSM8539255 MHCC97H-1-siMYC+MYC293D, MYC CUT-&TAG
- GSM8539256 MHCC97H-2-IgG, gG CUT-&TAG
- GSM8539257 MHCC97H-2-WT, MYC CUT-&TAG
- GSM8539258 MHCC97H-2-VRK2 KO, MYC CUT-&TAG
- GSM8539259 MHCC97H-2-VRK2 KO+MYC WT, MYC CUT-&TAG
- GSM8539260 MHCC97H-2-VRK2 KO+MYC281A, MYC CUT-&TAG
- GSM8539261 MHCC97H-2-VRK2 KO+MYC281D, MYC CUT-&TAG
- GSM8539262 MHCC97H-2-VRK2 KO+MYC293A, MYC CUT-&TAG
- GSM8539263 MHCC97H-2-VRK2 KO+MYC293D, MYC CUT-&TAG
- GSE279619 SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation. 124 samples
- GSE282258 Imaging-based drug screening combined with moleuclar profiling identifies signatures and drivers of therapy resistance in pediatric AML [ATAC-seq] 44 samples
- GSE294275 Transcriptional analysis of direct NSD2 target genes in t(4;14) multiple myeloma reveals H3K36me2-dependent regulation and H3K27me3 antagonism [CUT&TAG] 40 samples
- GSE267597 AP-1 Mediates Oncogenic Transcription and Predicts Fatality in Lung Squamous Cell Carcinoma Patients [ChIP-seq] 36 samples
- GSE308983 Reprogramming lineage features promotes epithelial behavior in carcinoma cells [ChIP-Seq] 23 samples
- GSE329512 SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry 19 samples
- GSE267470 Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma [CUT&RUN] 12 samples
- GSE316989 Targeting CDK12/CYCLIN K induces a gene activation program which is mediated by P-TEFb [Cut&RUN] 10 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.