KMT2C Deficiency Drives Luminal Transdifferentiation into Double-Negative Prostate Cancer and Sensitizes to Fatty Acid Synthase Inhibition [CUT&Tag]

Direct links to NCBI, no account and no request form: the whole study as GSE267775_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 26 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1112845 and SRA study SRP511353. Searching any of these in the dataset finder brings you back here.

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+ 26 more — browse all 26 samples with per-sample file links →

• GSE232552 FOXA2/AP-1 drives prostate cancer lineage plasticity [ChIP-seq] 24 samples
• GSE289247 Crosstalk between the polycomb repressive complex 2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity [ChIP-Seq] 35 samples
• GSE261351 Direct measurement of RNA Polymerase II hypertranscription in cancer FFPE samples 278 samples
• GSE245731 HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ChIP-seq] 172 samples
• GSE292300 A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer: ChIP-seq 76 samples
• GSE254753 Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors (ATAC-Seq) 45 samples
• GSE294572 HNF4a controls growth, identity and response to KRAS inhibition in IMA [ChIP- seq] 38 samples
• GSE270774 MYC couples SWI/SNF and metabolic reprogramming to sustain minimal residual disease in mTORC1-activated cancer cells [CUT&RUN, ATAC-seq] 32 samples

Search all ChIP / ATAC / CUT&Tag datasets in GEO →