A p53-CCF circuit integrates genome integrity with senescence phenotypes
Direct links to NCBI, no account and no request form: the whole study as GSE259308_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 81 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1080613 and SRA study SRP491802. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 40 samples.
10 replicated groups read from the first 40 of 81 sample titles; they account for 40 of them. Check it against the sample list below before relying on it.
- GSM8113395 IMR90 cells, proliferating, empty vector, rep 1
- GSM8113396 IMR90 cells, proliferating, empty vector, rep 2
- GSM8113397 IMR90 cells, proliferating, empty vector, rep 3
- GSM8113398 IMR90 cells, proliferating, 53BP1 OE, rep 1
- GSM8113399 IMR90 cells, proliferating, 53BP1 OE, rep 2
- GSM8113400 IMR90 cells, proliferating, 53BP1 OE, rep 3
- GSM8113401 IMR90 cells, IR, empty vector, rep 1
- GSM8113402 IMR90 cells, IR, empty vector, rep 2
- GSM8113403 IMR90 cells, IR, empty vector, rep 3
- GSM8113404 IMR90 cells, IR, 53BP1 OE, rep 1
- GSM8113405 IMR90 cells, IR, 53BP1 OE, rep 2
- GSM8113406 IMR90 cells, IR, 53BP1 OE, rep 3
- GSM8113410 vehicle, 20 months, female, rep 1
- GSM8113411 vehicle, 20 months, female, rep 2
- GSM8113412 vehicle, 20 months, female, rep 3
- GSM8113413 vehicle, 20 months, female, rep 4
- GSM8113414 HDM201, 20 months, female, rep 1
- GSM8113415 HDM201, 20 months, female, rep 2
- GSM8113416 HDM201, 20 months, female, rep 3
- GSM8113417 HDM201, 20 months, female, rep 4
- GSM8113418 HDM201, 20 months, female, rep 5
- GSM8113419 vehicle, 24 months, male, rep 1
- GSM8113420 vehicle, 24 months, male, rep 2
- GSM8113421 vehicle, 24 months, male, rep 3
- GSM8113422 vehicle, 24 months, male, rep 4
- GSM8113423 vehicle, 24 months, male, rep 5
- GSM8113424 HDM201, 24 months, male, rep 1
- GSM8113425 HDM201, 24 months, male, rep 2
- GSM8113426 HDM201, 24 months, male, rep 3
- GSM8113427 HDM201, 24 months, male, rep 4
- GSM8113428 HDM201, 24 months, male, rep 5
- GSM8113429 vehicle, 5 months, male, rep 1
- GSM8113430 vehicle, 5 months, male, rep 2
- GSM8113431 vehicle, 5 months, male, rep 3
- GSM8113432 vehicle, 5 months, male, rep 4
- GSM8113433 vehicle, 5 months, male, rep 5
- GSM8113434 vehicle, 5 months, female, rep 1
- GSM8113435 vehicle, 5 months, female, rep 2
- GSM8113436 vehicle, 5 months, female, rep 3
- GSM8113437 vehicle, 5 months, female, rep 4
+ 41 more — browse all 81 samples with per-sample file links →
- GSE278959 Genome-wide DNA replication profiling and full-length total RNA sequencing from the same single cell 546 samples
- GSE320162 Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity [RNA-Seq] 347 samples
- GSE293172 Pioneer factors orchestrate tissue-specific cohesin-NIPBL chromatin entry and 3D genome organization [ChIP-seq] 68 samples
- GSE320165 Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity [Cut&Tag] 46 samples
- GSE267117 scHiCAR: a tri-modal single-cell genomics technology for integrated transcriptome, epigenome, and 3D genome analysis in complex tissues [cellline_scHiCAR] 34 samples
- GSE247833 Genome organization around nuclear speckles drives mRNA splicing efficiency 26 samples
- GSE245949 Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer 24 samples
- GSE270175 Oxysterol Sensing through GPR183 Triggers Endothelial Senescence and Cardio-renal Injuries via Altering Circadian Signaling in Hypertension 18 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.