Bioinformatics Scientist, Assay Design and Pipelines

Bioinformatics Scientist

We are seeking a skilled and motivated Bioinformatics Scientist to join our team, specializing in assay and content development for qPCR, dPCR, and CE technologies. The role focuses on delivering high-quality assays on schedule and contributing to the development and maintenance of computational pipelines, databases, and infrastructure to scale assay development. This position requires strong domain knowledge of genomics, PCR-based methods, and proficiency in bioinformatics pipeline development. You will convert biological questions into assay strategies and assign robust primer/probe sets. You will streamline workflows and optimize code for efficiency and scalability. Collaboration with other bioinformatics scientists, product management, and customer support colleagues is essential.

Primary Responsibilities

• Design, develop, and optimize qPCR assays for various applications, including gene expression, genotyping, copy number analysis, and pathogen detection.
• Analyze and interpret complex genomic and sequence data to support target selection and assay development.
• Prepare and present scientific reports and presentations to communicate findings and progress.
• Develop, maintain, and optimize bioinformatics pipelines and workflow automation for large-scale assay development.
• Maintain version-controlled repositories, documentation, and reproducibility across computational workflows.
• Participate in the publication or productization of developed algorithms, pipelines, or tools

  Required Qualifications

  • PhD, Master or Bachelor's degree in Bioinformatics, Computational Biology, Molecular Biology, Bioinformatics, or related fields. Preferred with 2+ years of relevant experience.
  • Strong genomics & molecular biology domain knowledge in at least one of the domains in plant, mammalian, microbial, and oncology systems.
  • Bioinformatics stack: IGV, BLAST, BWA/other aligners; major databases (GenBank, Ensembl); experience across genomics, and quantitative data with strong analytical, problem-solving skills.
  • Strong programming for scripting: advanced Python and working R, solid debugging.
  • Teaming & execution: excellent communication; effective cross-functional collaboration; able to work independently and manage multiple projects concurrently.

    Preferred Qualifications

    • Experience in C/C++/Java/Perl/JavaScript/ReactJS; solid debugging.
    • Experience with other assay development platforms, such as NGS, microarrays, etc.
    • Familiarity with workflow orchestration frameworks (Nextflow, Snakemake, Latch) or cloud computing and high performance computing environments.

      At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.